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Old 07-31-2012, 09:26 PM
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Default Request for a thread similar to the opiate potentiation thread

primarily one that deals with taking certain supplements/otc medicines to help stave off and get through withdrawals, as well as perhaps methods for controlling an OD/uncomfortably too high as well as what to take to help ward off unpleasant side effects like nausea, constipation, etc.

the only one i can really provide any input on is dealing with nausea. If i have the luxury, ill take an ondansetron wafer under the tongue and this shit works miracles for some of the worst nausea ive had, and is pretty easily available from online pharmacies.

If i need an OTC medicine, Nauzene works great and pretty fast too.

please leave any ideas/tips here and once we have a sizable portion of info ill edit it into one nice little easy to read format and have a mod change the name of this thread or start another, as well as add it to the BLTC experiments thread.

thanks mawfackas
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Old 07-31-2012, 11:57 PM
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Default Re: Request for a thread similar to the opiate potentiation thread

bumpo
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Old 08-01-2012, 01:16 AM
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Default Re: Request for a thread similar to the opiate potentiation thread

Well we can't have a thread like this without mentioning immodium. Loperamide is a peripherally acting MOR agonist that helps with the diarrhea lol, no and some associated symptoms.

For nausea, I've found that ginger gum/extract works pretty well. Sure, it's not odansetron, but I find it works decently in about 15 minutes.

Alternatively, take up figging

Last edited by Gun Lover; 08-01-2012 at 12:50 PM. Reason: derp
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Old 08-01-2012, 01:46 AM
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Default Re: Request for a thread similar to the opiate potentiation thread

does figging have any actual health pros to it or is it just anal sexy fun?
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Old 08-01-2012, 01:51 AM
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Thumbs Up Re: Request for a thread similar to the opiate potentiation thread

Quote:
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does figging have any actual health pros to it or is it just anal sexy fun?
I'm guessing it'd take away any nausea probably more effectively than if you ate it. Beware it burns
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Old 08-01-2012, 02:54 AM
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Default Re: Request for a thread similar to the opiate potentiation thread

As soon as it develops into something I'll be sure to throw it into the link thread.

In the meantime, I'll throw some stuff in here as I think of it. I've found from countless bottles of cough syrup consumed, laying on your back with your head and neck raised by two or three pillows works pretty well for nausea if you don't have any medicines/while you wait for them to kick in.
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Old 08-01-2012, 02:56 AM
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Default Re: Request for a thread similar to the opiate potentiation thread

For your opioid-induced constipation after a weekend binge - bisacodyl. I have never shit so much in my life.
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Old 08-01-2012, 09:46 AM
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Default Re: Request for a thread similar to the opiate potentiation thread

For that constipation eat some nutella. Taste good as fuck and gives you the shits lol.
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Old 08-01-2012, 07:34 PM
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Default Re: Request for a thread similar to the opiate potentiation thread

if youve got a major blockage (i.e. a giant rock of turdshit) is there any danger in taking an anti-constipatory? like could your intestines pop or some shit.
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Old 08-01-2012, 10:16 PM
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Default Re: Request for a thread similar to the opiate potentiation thread

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Originally Posted by GreatestGatsby4 View Post
if youve got a major blockage (i.e. a giant rock of turdshit) is there any danger in taking an anti-constipatory? like could your intestines pop or some shit.
No, in fact, the best thing to do is take laxatives. The kind that don't clump it all together and make you shit it all at once.

TMI ahead:

I always hated shitting so when I was like 5 I thought fuck it, I just won't shit anymore. A few weeks into this brilliant idea, my intestines were rock fucking solid and in immense pain.

Eventually I was taken to the ER and they gave me this suppository and a disposable toilet because they knew there was no way it would flush in a regular one.

Baby elephants take smaller shits than I did that day


So yeah, laxatives. Polyethylene glycol/ castor oil/ magnesium citrate
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Old 08-01-2012, 10:48 PM
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Default Re: Request for a thread similar to the opiate potentiation thread

how much magnesium citrate? i have a bottle around that i use to control tolerance as per the Opiate potentiation thread
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Old 08-01-2012, 11:04 PM
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Default Re: Request for a thread similar to the opiate potentiation thread

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how much magnesium citrate? i have a bottle around that i use to control tolerance as per the Opiate potentiation thread
I can't really tell you, unfortunately. They sell generic versions in about 12oz bottles, and they recommend you drink it all.

I've had results with a quarter bottle, but I wasn't experiencing ope constipation .

Even though it makes you shit, the extra magnesium always seems to lift my mood noticeably. Oh, but Casper reminded me that it will make you feel bloated as shit due to extra water absorption. I'm sorry, he literally mentioned this yesterday. Get some mineral/castor oil or polyethylene glycol (miralax).

Last edited by Gun Lover; 08-01-2012 at 11:08 PM.
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Old 08-02-2012, 01:57 AM
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Default Re: Request for a thread similar to the opiate potentiation thread

A while back I came across this guide of several methods to potentiate an opiate high. I did not write this myself but it really does work well. I reccomend this thread be stickied.....my bad if this has been posted before...



"Hi BLTC!

try N0 W4RN1NG's patented opioid potentiation formula:

* T-45) 600mg Tagamet HB(Cimetidine HCl), a large glass of tonic water (or another source of quinine), and a large glass of (white) Grapefruit juice, preferably from concentrate.
* T-35) 30mg DXM HBr, 4mg CPM, 25mg Benadryl(Diphenhydramine HCl), 330mg Naproxen(Aleve).
* T-20) 2 Tums OR 1.5 Tbsp. of Baking SODA. (Obviously this step only applies if you are eating your opes)
* T-0) Parachute\chew\rail\bang your opiate\opioid.
* T+10) Smoke a bowl or two. Not more, you don't want to over power it.

In depth explanation:

The Tagamet HB (Cimetidine) is a broad CYP450 inhibitor. This basically means it 'clogs' the enzymes that metabolize opiates\opioids and clear 'em out of the body. Tagamet HB tablets are 200mg each, so the recommended 600mg is 3 tabs. They're OTC, and you can get a box of 50 generic 200mg cimetidine tabs at CVS for like $5.49.

Quinine is an ingredient in tonic water, and functions the same way as Tagamet. It inhibits the CYP450 set, more specifically, CYP2D6. It doesn't 'clog' as many enzymes as Tagamet does, but it STRONGLY 'clogs' CYP2D6, which is the MAIN enzyme for opiates like oxycodone, heroin, hydromorphone, etc. A large glass of straight tonic water is plenty. I prefer the "Vintage" brand. You can buy a liter of tonic water at any grocery for like $2.00.

White grapefruit juice contains three ingredients that clog the CYP450 set. However, it doesn't clog CYP2D6 too well, which is the main one for most opes. It does strongly 'clog' CYP3A4 nicely though, and although that's almost an 'auxillary' enzyme for alot of opiates, it definitely helps out. Again, it's cheap. Go to any grocery store and you should be able to get a nice big bottle of 100% whitre grapefruit juice from concentrate for like $2.50-$3.50.

An important thing to note for the grapefruit juice is the percentage of juice. A lot of companies make "White grapefruit juice" that is basically water, corn syrup, and like 10% juice. This is almost a waste of your money. You want it to say 100% juice, and also, you want to make sure it's 100% white grapefruit juice! A very common business practice for juice companies is to create 'juice cocktails'. These are beverages that are MAINLY cheap filler juices like apple and pear, with the advertised fruit only partially accounting for that '100% juice' the bottle sports so vividly. Look in the ingredients list, and make sure the only juice in there is white grapefruit, preferably from concentrate.

Nutritionally, juices from concentrate are usually not as good. However, for one reason or another, grapefruit juice from concentrate can contain 25%-40% MORE naringin, bergamottin and dihydroxybergamottin; the three enzyme inhibitors present in white grapefruit.

Now, some of you may be wondering WHY 'clogging' these enzymes is so beneficial. Basically, by slowing or even completely stopping the metabolization of opiates, they last MUCH longer. Also, blood plasma levels of opiates have been shown to vastly higher when the CYP450 set is strongly inhibited; meaning their is a higher peak, and it lasts longer.

It's a win-win situation, trust me. ^_^

On to the other shit. Benadryl(diphenhydramine HCl) and CPM(chlorpheniramine maleate) are both over-the-counter anti-histamines that increase the analgesic and euphoric properties of opiates to some extent. They also help cut down on the ope-itch. In addition, these guys also slightly inhibit subset CYP2D6.

Seeing a pattern here?

DXM (Dextromethorphan HBr, Robitussin, Zicam, etc.[not that it needed an intro on this board]) has a special effect in this formula. Although it doesn't inhibit the CYP450 set to any appreciable extent, it does contribute to analgesia and euphoria for all major opiates. Also, it has been shown to prevent the build up of tolerance! 30mg of DXM a good half hour or so before dosing will definitely slow any tolerance build up if you use this method every time. And with opiates, that's a VERY big deal.

The Naproxen(Aleve) adds to the analgesia and euphoria. Aleve comes in 220mg tabs, so by 330mg I mean one-and-a-half tabs.

The tums\baking soda is only necessary if you're eating the opiates in question. Basically, they lower the PH of the stomach\GI tract [well, technically it raises the PH, but ya know what I mean] which allows more of the opiate to be absorbed into the blood.

It's fine to smoke a little bud, but too much ruins the high IMO. And when I say a little, I mean like .2g, tops. If you have a moster tolerance, titrate accordingly, but if you smoke a few times a week .3 will be perfect.

To further breakdown all this pre-dose potentiation, I'll make it easy for you guys and just tell ya how many pills to take, and the exact way I consume them

* T-45) 3 200mg Cimetidine pills, washed down with a HUGE tonic water\white grapefruit juice cocktail.
* T-35) 1 Coriciden Cough & Cold Low Blood Pressure, 1 Benadryl, and one and a half Aleve.
* T-20) 2 extra strength Tums if I'm popping the opes.
* T-0) Rail\pop those shits.
* T+10) *Smokes a bowl*

The Coriciden has both 30mg of DXM and 4 mg of CPM, so it's good for killin' 2 birds with one stone. No pun intended.

Also, some people are under the impression that all these drugs make the high "dirty". They CAN, no doubt about it, but in the dosages I listed, there are *NO* perceived changes in the quality of the high. It really does feel like you took more opiate, minus some itching.

Anyway, that's basically it! Hope I manage to help some of you guys out on your voyages to the land of nod, and if you have any questions, feel free to post.

And if this is too lengthy, it's because I'm yakked out of my skull PLUS 48mg hydromorphone; preloaded, of course, with my all-powerful formula.

...and I'm procrastinating for a paper due tomorrow morning. But that's besides the point. Peace!

N0 W4RN1NG

EDIT: Forgot to mention:

This formula should NOT be used in combination with codeine. Codeine's pleasurable effects are largely dependant on it's metabolization into morphine via CYP450 subsets. This formula basically fucks that shit up the ass. If you're using codeine, just take the DXM.

Also, if you plan on drinking alcohol, nix the Aleve. It can cause some nasty damage to your stomach in combo with alcohol. Same goes for APAP\Tylenol(acetaminophen), so if you're taking opiates with tylenol included (Vicoden, Percoset, Endocet, Tylenol 3, etc) be nice to your liver and don't drink. Liver failure is no picnic, mkay?"


-Once again...I did not write this guide.

I took 3 percocets last night and used this method it felt like I took 6
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Old 08-02-2012, 02:29 AM
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Default Re: Request for a thread similar to the opiate potentiation thread

That method works very well, but Admech has a more updated one around here, that should be stickied, or added to the experiment thread. And also I think it says somewhere that depending on whether you're using oxy or a morphine derived ope, some don't work as well
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Old 08-02-2012, 12:25 PM
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Default Re: Request for a thread similar to the opiate potentiation thread

While T-45 sounds interesting, Tagamet has been removed from a lot of markets. It might be hard to find.

Oh, and it gives you bitch-tits.
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Old 08-02-2012, 05:54 PM
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Default Re: Request for a thread similar to the opiate potentiation thread

Admechs thread is on the experiments thread already. Back when I tried really hard to potentiate as hard as I could, Ive still NEVER been able to find Tagamet or a generic ANYWHERE.
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Last edited by Thetakishi; 08-02-2012 at 05:58 PM.
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Old 08-02-2012, 07:18 PM
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Default Re: Request for a thread similar to the opiate potentiation thread

ways to bring someone out of an OD

-IV either naltrexone or bupe. yes bupe. seriously, it works. old trick.


ways to stave off w/d's

-HIGH MEGA dose immodium. add some dxm [30-60mgs] if needed, cannabis and or alcohol.


best way to get higher?

-do more of your opiate of choice.



[sad but all are true].....




one way one could beat W/D is to use stimulants from day 1-day 5. crash, eat lots of valium. sleep. rinse lather repeat [well cut down the tweak days to 48 hours at most a go]. you regardless don't sleep right for a while. get a hobby, you aint gonna sleep and you'll have tons of time on your hands now that your not nodding out droolin up a puddle.
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Old 08-02-2012, 08:03 PM
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Default Re: Request for a thread similar to the opiate potentiation thread

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ways to bring someone out of an OD

-IV either naltrexone or bupe. yes bupe. seriously, it works. old trick.

one way one could beat W/D is to use stimulants from day 1-day 5. crash, eat lots of valium. sleep. rinse lather repeat [well cut down the tweak days to 48 hours at most a go]. you regardless don't sleep right for a while. get a hobby, you aint gonna sleep and you'll have tons of time on your hands now that your not nodding out droolin up a puddle.
The bupe thing is true. That's why I'm glad I have an excess of suboxone. I'm going to be someone's hero someday if they OD.

If I used stimulants on any WD day besides 1 or after 4, I'd probably shoot myself. Although I have thought of that plan for very light WD's before.
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Old 08-02-2012, 08:17 PM
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Default Re: Request for a thread similar to the opiate potentiation thread

Quote:
Originally Posted by GreatestGatsby4 View Post
if youve got a major blockage (i.e. a giant rock of turdshit) is there any danger in taking an anti-constipatory? like could your intestines pop or some shit.
YES

Quote:
Originally Posted by Gun Lover View Post
No, in fact, the best thing to do is take laxatives. The kind that don't clump it all together and make you shit it all at once.

TMI ahead:

I always hated shitting so when I was like 5 I thought fuck it, I just won't shit anymore. A few weeks into this brilliant idea, my intestines were rock fucking solid and in immense pain.

Eventually I was taken to the ER and they gave me this suppository and a disposable toilet because they knew there was no way it would flush in a regular one.

Baby elephants take smaller shits than I did that day


So yeah, laxatives. Polyethylene glycol/ castor oil/ magnesium citrate
Dude Im sorry but no. All but magnesium citrate. Some of us for one reason or another decide to be complete fuckwits and do multiple grams of opiates a day. At one point i hadnt shit in 6 or 7 days, and I took a small, 1/2 dose of epsom salts. The pain was SO immense...probably the worst Ive felt in my life. Felt like my insides were splitting. Come to look at the method of action later...and a lot of laxatives movethe blockage my drawing water into the colon. Well if you can imagine...if for whatever reason that blockage doesnt go anywhere (although theyre assuming youre NOT on incredible amounts of opioids), then your insides swell with water to the point of bursting.

So yes, it can be very dangerous. I hope everyone who does opiates reads that. I'm a 300 lb grown man- 6' 7"...and I was curled up on my living room floor in the fetal position, bawling like a baby.

First course of action needs to be stool softeners, fiber, and LOTS of water...especially if you suspect you might have a major blockage.

Her-oin shits ain't nothin' to fuck wit
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Old 08-02-2012, 08:41 PM
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Default Re: Request for a thread similar to the opiate potentiation thread

All but magnesium citrate are good, or bad?
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Old 08-02-2012, 09:51 PM
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Default Re: Request for a thread similar to the opiate potentiation thread

Good...i think. Im pretty sure propylene glycol is MiraLax or glycerine- and mineral oil- are both softeners.

The action of magnesium changes the electrolyte balance or whatever and draws water into the colon by osmosis...so thats the only one i think would be dangerous. The others just soften or grease the runway as it were.
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Old 08-02-2012, 09:59 PM
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Originally Posted by Thetakishi View Post
Admechs thread is on the experiments thread already. Back when I tried really hard to potentiate as hard as I could, Ive still NEVER been able to find Tagamet or a generic ANYWHERE.
Well, yeah. It gives you bitch tits. What more do you need?
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Old 08-02-2012, 11:54 PM
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Quote:
Originally Posted by General Butt.Naked View Post
Dude Im sorry but no. All but magnesium citrate. Some of us for one reason or another decide to be complete fuckwits and do multiple grams of opiates a day. At one point i hadnt shit in 6 or 7 days, and I took a small, 1/2 dose of epsom salts. The pain was SO immense...probably the worst Ive felt in my life. Felt like my insides were splitting. Come to look at the method of action later...and a lot of laxatives movethe blockage my drawing water into the colon. Well if you can imagine...if for whatever reason that blockage doesnt go anywhere (although theyre assuming youre NOT on incredible amounts of opioids), then your insides swell with water to the point of bursting.

So yes, it can be very dangerous. I hope everyone who does opiates reads that. I'm a 300 lb grown man- 6' 7"...and I was curled up on my living room floor in the fetal position, bawling like a baby.

First course of action needs to be stool softeners, fiber, and LOTS of water...especially if you suspect you might have a major blockage.

Her-oin shits ain't nothin' to fuck wit
I bow to your wisdom. I'll never recommend Mg citrate to someone in ope WD.

Thanks for the thorough schooling
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Old 08-03-2012, 12:47 AM
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Default Re: Request for a thread similar to the opiate potentiation thread

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Originally Posted by Gun Lover View Post
I can't really tell you, unfortunately. They sell generic versions in about 12oz bottles, and they recommend you drink it all.

I've had results with a quarter bottle, but I wasn't experiencing ope constipation .

Even though it makes you shit, the extra magnesium always seems to lift my mood noticeably. Oh, but Casper reminded me that it will make you feel bloated as shit due to extra water absorption. I'm sorry, he literally mentioned this yesterday. Get some mineral/castor oil or polyethylene glycol (miralax).
Oh Casper, you must've missed my edit, I already saw you school me on Mg citrate in the ask a MD thread. I don't forget things that quick.
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Old 08-03-2012, 03:46 AM
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Default Re: Request for a thread similar to the opiate potentiation thread

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Oh Casper, you must've missed my edit, I already saw you school me on Mg citrate in the ask a MD thread. I don't forget things that quick.
'Sall gravy playa! I didnt remember who exactly it was in the MD thread...was actually gonna go back n copypasta...but yes, my laziness does extend that far. Just want to make sure no one has go go through that...a whole new level of NOT FUN. The other two suggestions are gravy though.
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