Is weed dangerous?

[Aperson444]

I'm trying to come up with a framework/philosophy to figure out what I should do basically. Maybe I should appreciate every small thing that happens in life, and that would make me happy, and I wouldn't need to resort to drugs?

Good luck with that. Humans are incredibly narrow minded and ignorant. Drugs appear to heighten that appreciation of little things.

[mexico]

Any mod who reads this can you please check on the status of resetting my password to my old account? Sky said he was checking on it but I haven't heard back. I don't want to lose an acct that's 5 years old and has over 5k posts

[Rainycity]

Originally Posted by ShutMeUp

dude you're 20 or something.

Fixt, still 5 years of smoking is long. Plus the last year, ive been high almost every second. So im going say, im no noob.

[mexico]

How long someone has been smoking weed has little bearing on how much they know about the pharmacology of the plant

[Rainycity]

Originally Posted by a334jv2df #2

How long someone has been smoking weed has little bearing on how much they know about the pharmacology of the plant

im the Guinea pig, i know enough.

[Xavier-]

Are there GENUINELY people in this thread denying that cannabis has the potential to cause psychosis?

Such a well worded response, but my god.......



Edit: Also, for the record, nobody ever said correlation=causation. Every major medical study into this to date however HAS suggested a link. It might not be concrete but it's the best we've got at the moment. Denying the risk is even there is quite frankly fucking stupid.

[Xavier-]

Originally Posted by a334jv2df #2

blah blah blah

You may not be trying to be an asshole, but quite frankly you are anyway.

Firstly i'll say this, i never pretended to be an expert, i'm merely offering advice from an experienced point of view, as for the rest of what you've said here, you're talking a bunch of shit gleamed from reading wikipedia so i'm not even going to try and approach any of that, what i will do however is post links to the COUNTLESS studies that have suggested links between cannabis use and schizophrenia or psychosis, these are very easily found so it's no hassle for me.

http://www.ncbi.nlm.nih.gov/pubmed/2892048

http://www.bmj.com/content/325/7374/1212.full

http://md1.csa.com/partners/viewreco...&setcookie=yes

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3181719/

Those are but a few, are any of them definitive? No, what, sorry........did you expect me to prove something that hasn't actually been definitively proven yet? Shit, there's me thinking i was just suggesting the possibility.

Best start reading huh kid, there's alot there.

Seriously this link has been suggested for decades i'm in awe of the fact some of you refuse to accept even the possibility that there is a causal link.

Armchair experts the lot of you.

[Township Rebellion]

^^^ It's funny to go through all this trouble only for those links to state specifically that marijuana is more dangerous to minors, teenagers with still-developing brains. Also, cases seem to be fairly rare.

So, to me, you're making a mountain out of a molehill. I don't suffer from schizophrenia, most people who smoke weed likely won't - but it should be their decision to take that risk.

[Doki66]

Originally Posted by trolly

Cuz I'm a pussy and I'm trying not to fuck up my brain but I smoked again last night and it was the most amazing feeling ever

and plus I was insanely smart.. it was crazy...

can't remember shit though

But realistic question.. anyone know anyone who has long term negative effects from smoking constantly?

[Aperson444]

Firstly i'll say this, i never pretended to be an expert, i'm merely offering advice from an experienced point of view, as for the rest of what you've said here, you're talking a bunch of shit gleamed from reading wikipedia so i'm not even going to try and approach any of that, what i will do however is post links to the COUNTLESS studies that have suggested links between cannabis use and schizophrenia or psychosis, these are very easily found so it's no hassle for me.

I'm somewhat doubtful of a causal relationship between psychosis and cannabis. First off, there have been numerous psychopharmacological studies that have failed to find a neurochemical link between psychosis and cannabis use (i.e the Nutt study on dopamine receptor agonism in the striatum). Secondly, I have noticed that people who are prone to or suffer from mental illness tend to gravitate towards cannabis. Why? I can't tell, but pre-psychotic and depression-prone individuals appear to begin smoking more than those with normal mental health.

Furthermore there is some increasing evidence that cannabis may provide ANTI-psychotic properties, so much so that some cannabinoids are as effective at treating psychosis as prescription atypical antipsychotics.

I'd prefer psychosis over severe boredom anyways. I don't think it really means much that there's a correlation between cannabis use and psychosis. Quite frankly, even if there was a causal relationship, I would not give two shits and I would still continue to encourage cannabis use.

[mexico]

Originally Posted by Xavier-

You may not be trying to be an asshole, but quite frankly you are anyway.

Firstly i'll say this, i never pretended to be an expert, i'm merely offering advice from an experienced point of view, as for the rest of what you've said here, you're talking a bunch of shit gleamed from reading wikipedia so i'm not even going to try and approach any of that, what i will do however is post links to the COUNTLESS studies that have suggested links between cannabis use and schizophrenia or psychosis, these are very easily found so it's no hassle for me.

http://www.ncbi.nlm.nih.gov/pubmed/2892048

http://www.bmj.com/content/325/7374/1212.full

http://md1.csa.com/partners/viewreco...&setcookie=yes

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3181719/

Those are but a few, are any of them definitive? No, what, sorry........did you expect me to prove something that hasn't actually been definitively proven yet? Shit, there's me thinking i was just suggesting the possibility.

Best start reading huh kid, there's alot there.

Seriously this link has been suggested for decades i'm in awe of the fact some of you refuse to accept even the possibility that there is a causal link.

Armchair experts the lot of you.

Armchair expert, huh? I've been posting on BLTC totse/zok since 1999.... Almost 14 years... In that 14 years I've been a psychoactive guinea pig, as well as picking up a BSc in a hard science and working in the RC industry as a broker for a few years. I've been smoking weed for 15 years as well.

But, like I said, non of that matters. You won't "even touch" what I said because you can't. Its funny how you admit nothing you posted is definitive, claim there is no definitive answer, yet remain steadfast in your unjustified conviction that marijuana causes x y z. You don't even know what the disease model is nor did you know what the DSM IV. Anyone offering "an experienced opinion" would know such things.

Again, I'm not saying marijuana doesn't cause any mental illness. I'm saying that it is NOT DEFINITIVELY documented. I am however calling you a fucking moron. Don't take it to seriously though I'm convinced you're just a kid. So, again, lurk more before you post kidiot

[Synopix]

Watch out, Its insanely dangerous!

[kingOfCrash]

Originally Posted by Township Rebellion

^^^ It's funny to go through all this trouble only for those links to state specifically that marijuana is more dangerous to minors, teenagers with still-developing brains. Also, cases seem to be fairly rare.

So, to me, you're making a mountain out of a molehill. I don't suffer from schizophrenia, most people who smoke weed likely won't - but it should be their decision to take that risk.

Your anecdotal evidence doesn't devalue the empirical evidence of the correlation between cannabis use and mental illness. It's obviously not widespread among users or else cannabis wouldn't be such a popular drug. His argument wasn't that it a common feature of cannabis users or that they shouldn't be allowed to make the decision.

To the question that "is weed dangerous?" The answer is yes. More so to adolescents (even beyond being a minor).

From a more biological perspective, however, use of cannabis during critical developmental periods in the still maturing brain may induce persistent alterations in brain structure and brain function. Therefore, the effects of frequent cannabis use during adolescence could be different from and more serious than during adulthood, an issue increasingly recognized in the field of cannabis research.

http://www.ncbi.nlm.nih.gov/pubmed/19630711

So trolly, there is more than enough evidence here to suggest that you shouldn't be smoking pot. Wait until you're older. Depression and angst is fucking normal for a teenager and not a sign of any form of disorder.

[Xavier-]

Originally Posted by Aperson444

Furthermore there is some increasing evidence that cannabis may provide ANTI-psychotic properties, so much so that some cannabinoids are as effective at treating psychosis as prescription atypical antipsychotics.

Quite frankly, even if there was a causal relationship, I would not give two shits and I would still continue to encourage cannabis use.

There's also been a lot of evidence that anti-psychotic properties are being bred out of the plants and that cannabis today is showing an increase in THC with a decrease in CBD. As for you 'continuing to encourage cannabis use" that just shows what a fucking idiot you are.

Originally Posted by a334jv2df #2

Armchair expert, huh? I've been posting on BLTC totse/zok since 1999.... Almost 14 years... 've been smoking weed for 15 years as well.

Posting on a forum doesn't make you an expert ya daft cunt.

But, like I said, non of that matters. You won't "even touch" what I said because you can't. Its funny how you admit nothing you posted is definitive, claim there is no definitive answer, yet remain steadfast in your unjustified conviction that marijuana causes x y z. You don't even know what the disease model is nor did you know what the DSM IV. Anyone offering "an experienced opinion" would know such things.

Again, I'm not saying marijuana doesn't cause any mental illness. I'm saying that it is NOT DEFINITIVELY documented. I am however calling you a fucking moron. Don't take it to seriously though I'm convinced you're just a kid. So, again, lurk more before you post kidiot

I won't touch what you've posted because frankly kid it's a crock of shit you copy/pasted from the internet in a vain effort to appear smarter than you are. As for not knowing about DSM IV good one buddy. Anyone with even a passive interest in psychology would, otherwise how the hell would YOU know what it is??

The only morons in here are you and the other dickhead denying that the heaps of evidence we've built up showing a possible link between cannabis and mental health issues is all bullshit.

YOU may not believe it, that doesn't mean it isn't true. There are as i've stated a million times an INFINITE number of studies all suggesting the same thing. Go read some of them and stop thinking you're an expert because you post a bunch of nonsense on a website and took drugs for a long time.

[Xavier-]

Originally Posted by kingOfCrash

Your anecdotal evidence doesn't devalue the empirical evidence of the correlation between cannabis use and mental illness. It's obviously not widespread among users or else cannabis wouldn't be such a popular drug. His argument wasn't that it a common feature of cannabis users or that they shouldn't be allowed to make the decision.

To the question that "is weed dangerous?" The answer is yes. More so to adolescents (even beyond being a minor).

Ding ding ding. We have a winner.

/thread before the 'experts' come back and talk out of their ass again.

[Xlite]

For some people it is, for others it ain't.

[Xavier-]

Originally Posted by Township Rebellion

^^^ It's funny to go through all this trouble only for those links to state specifically that marijuana is more dangerous to minors, teenagers with still-developing brains. Also, cases seem to be fairly rare.

Who constitute the majority of cannabis smokers......

So, to me, you're making a mountain out of a molehill. I don't suffer from schizophrenia, most people who smoke weed likely won't - but it should be their decision to take that risk.

No, what i'm doing is offering all the evidence i can to somebody curious about drug use, it doesn't matter whether one in a million is at risk, it's still a risk and it's still worth mentioning. As for it being their decision if you paid attention, you'd see i've been saying that.

[mexico]

You didn't even know that schizophrenia was classified under the disease model how could you possibly have even known of the disease concept or the dsm?

So far I have not seen a single shred of evidence supporting your claim. Is weed dangerous? Yea, smoking plant material is not a safe roa. Can marijuana smoke cause cancer? Maybe. Does marijuana cause cancer? No. Not if you vape it or eat it. End of thread. Thanks for playing.

Lol @ copy pasta. All you would have to do is plug a line or two into google to see its not a copy paste. Its all extremely basic pharmacology

[broseph]

insanely dangerous.

i took a drag, inhaled half of it and the next thing i wake up and everyone at the party is dead. drug-induced hysteria, they said. rape and murder, sixteen times over they said. am i mad? i don't feel mad. HEEHEEHAAHAAOOHAAHHE! EHEHEHEH! OAH! AHAHAHA! LALALA! LADADADA! DEE DEE DOO DOO!!

[Slayre]

Addition of delta-9-tetrahydrocannabinol or cannabinol to an incubation medium containing decapsulated mouse testes caused a significant reduction in the accumulation of testosterone in the medium. This result suggests that the reported effects of cannabis on male sexual and reproductive function may result from direct inhibition of testicular steroidogenesis by both psychoactive and nonpsychoactive constituents of marihuana.

http://www.sciencemag.org/content/196/4297/1472.short

Twenty heterosexual men 18 to 28 years of age who used marihuana at least four days a week for a minimum of six months without use of other drugs during that interval were studied. Mean (± S.E.M.) plasma testosterone — 416 ± 34 ng per 100 ml — was significantly lower in this group than that in the control-group mean — 742 ± 29 ng per 100 ml — for age-matched men who had never used marihuana. Decreased testosterone was dose related. Abstention from marihuana use and stimulation with human chorionic gonadotropin during continued marihuana use produced marked increases in testosterone. Measurements of liver function, circulating gonadotropins, prolactin, Cortisol and thyroxine were within normal limits. Six of 17 men (35 per cent) showed oligospermia, and two men were impotent. The data suggest that chronic intensive use of marihuana may produce alterations in male reproductive physiology through central (hypothalamic or pituitary) action

http://www.nejm.org/doi/pdf/10.1056/NEJM197404182901602

[Aperson444]

There's also been a lot of evidence that anti-psychotic properties are being bred out of the plants and that cannabis today is showing an increase in THC with a decrease in CBD.

Actually, that's near impossible. For starters, cannabidiol can be considered a precursor to THC. Looking at the molecular structure, CBD is only one step away from THC in terms of cyclization to form the tight little chromene ring.

Also, the medical marijuana movement has spurred a return of CBD in most strains. I wouldn't expect to see CBD vanish soon. You don't need a whole lot anyways.

http://www.nejm.org/doi/pdf/10.1056/NEJM197404182901602

http://www.nejm.org/doi/full/10.1056...97504172921615

and

http://www.sciencemag.org/content/213/4507/581.short

as well as

http://www.sciencedirect.com/science...7687169190068A

So, to sum it up, the hormone-cannabis link is too shaky to be taken in at all for reasons not to smoke.

As for you 'continuing to encourage cannabis use" that just shows what a fucking idiot you are.

Care to elaborate?

The only morons in here are you and the other dickhead denying that the heaps of evidence we've built up showing a possible link between cannabis and mental health issues is all bullshit.

At one point, in the 17th century, there was demonstrated a possible link between coffee consumption and drying up of cerebrospinal fluid, thus causing brain damage and death.

I won't touch what you've posted because frankly kid it's a crock of shit you copy/pasted from the internet in a vain effort to appear smarter than you are. As for not knowing about DSM IV

You yourself attempted to refute the idea that schizophorenia is a defined disease...

YOU may not believe it, that doesn't mean it isn't true. There are as i've stated a million times an INFINITE number of studies all suggesting the same thing. Go read some of them and stop thinking you're an expert because you post a bunch of nonsense on a website and took drugs for a long time.

You should read some studies from the other side as well. You should also attempt to look at neurochemical and biochemical mechanisms rather than attempting to interpret the entire field of psychology. Once you crack into more physical mechanisms for psychosis, you will find that there is only a loose possible causal relationship between cannabis and psychosis.

Caffeine, cocaine and amphetamine are far more likely to trigger psychosis than cannabis.

Who constitute the majority of cannabis smokers......

Says who? Your mom?

[Xavier-]

Originally Posted by mexico

You didn't even know that schizophrenia was classified under the disease model how could you possibly have even known of the disease concept or the dsm?

So far I have not seen a single shred of evidence supporting your claim. Is weed dangerous? Yea, smoking plant material is not a safe roa. Can marijuana smoke cause cancer? Maybe. Does marijuana cause cancer? No. Not if you vape it or eat it. End of thread. Thanks for playing.

Are you fucking kidding me

Originally Posted by Aperson444

Actually, that's near impossible. For starters, cannabidiol can be considered a precursor to THC. Looking at the molecular structure, CBD is only one step away from THC in terms of cyclization to form the tight little chromene ring.

Also, the medical marijuana movement has spurred a return of CBD in most strains. I wouldn't expect to see CBD vanish soon. You don't need a whole lot anyways.

So you say it's nearly impossible, then counter that medical marijuana has spurred a return of high CBD strains (which you're right it has). Way to contradict yourself there buddy.

Caffeine, cocaine and amphetamine are far more likely to trigger psychosis than cannabis.

Yes they are, but it's good to see you're finally accepting that Cannabis can, which really has been what this whole argument has been about, thanks for handing me that one on a plate there kid.

Says who? Your mom?

says statistics ya silly twat.

[Xavier-]

Anyway i'm literally done here, even if you want to assume that means you've won, i'm not going to spend my time arguing with people who think posting on a message board and using drugs makes them an expert.

All i've ever stated in this thread is that cannabis use comes with the risk of mental disorders developing, if you deny that you're a retard it's plain and simple.

[Xlite]

Originally Posted by Xavier-

Anyway i'm literally done here, even if you want to assume that means you've won, i'm not going to spend my time arguing with people who think posting on a message board and using drugs makes them an expert.

All i've ever stated in this thread is that cannabis use comes with the risk of mental disorders developing, if you deny that you're a retard it's plain and simple.

^True story.

[Aperson444]

So you say it's nearly impossible, then counter that medical marijuana has spurred a return of high CBD strains (which you're right it has). Way to contradict yourself there buddy.

No. I implied that it's nearly impossible that CBD will vanish. I never implied that THC wasn't being amplified in modern plants. The MMJ movement has brought attention upon CBD, so levels are rising. I said it's impossible to reach 0% CBD in all plants worldwide.

Don't put words in my mouth.

Yes they are, but it's good to see you're finally accepting that Cannabis can, which really has been what this whole argument has been about, thanks for handing me that one on a plate there kid.

There's a difference between correlation and causation. You of all people should know that. If you put my initial statement in context, you will realize that I'm referring to the dopaminergic/catecholamine hypothesis of psychosis. Cannabis, unfortunately for you, does not appear to possess any inherent neurochemical pathways with trigger psychosis. Note that I'm not trying to say that it cannot precipitate psychosis in predisposed individuals. Any sort of neurological severance will put vulnerable individuals at risk of some of the cognitive cycles associated with precipitation of psychosis.

says statistics ya silly twat.

Give a modern reference which explicitly states that the majority of cannabis users are adolescents which fall into the definition of adolescent according to your cited studies.

All i've ever stated in this thread is that cannabis use comes with the risk of mental disorders developing, if you deny that you're a retard it's plain and simple.

I don't think very many people have come out and blatantly denied that. What they're trying to argue is that there is no causal relationship associated with cannabis and psychosis; all existing hypotheses concerning this link utilize correlational data which is unreliable and insignificant.

ITT: A troll attempts to irritate some retarded BLTC stoners. Plan backfires, and asshat gets butthurt. Asshat then rage quits and sulk off to go masturbate to Goatse.

[meateor]

You'll be fine man, mary jane is a nice lady, she never hurt nobody. Just treat her with respect and dignity like you ought to treat any fine woman, and she'll treat you just as well

[Figure-8]

Cannabis use amplifies disorders that you already have. In a way that's showing them to you, too.

[mexico]

Ah yes! He left. To bad he didn't share his expert credentials before he left

[Aperson444]

Cannabis use amplifies disorders that you already have. In a way that's showing them to you, too.

I have most certainly found this. It's a very reasonable hypothesis to, considering that cannabis acts like an amplifying agent for some neural circuits and a dimming agent for others. I find that smoking while you are actively depressed or mentally disturbed will worsen the situation, but smoking when you're in a "content" phase or when you feel moderately happy can amplify, moderate and elongate the period of happiness. In some cases, I've noted that smoking during one of these "content" phases can combat my severe depressive phases for a week or more afterwards, with little to no rebound depression.

One should also note that people who are later diagnosed with psychosis often demonstrate distinct "pre-psychotic" symptoms; especially those with a family history of psychotic disorders. Cannabis use during a "pre-psychotic" episode is thus unwise.

[Figure-8]

Basically the danger of marijuana is the mental effect. A generally non-disturbed person can develop anxiety symptoms and even substantially traumatic episodes of panic.

That's why everything requires respect. If you are in a medical state, your Dr. will inform you of this. If a medicine is potent enough it will have to be limited to some degree.

[Vizier]

Originally Posted by Figure-8

Basically the danger of marijuana is the mental effect.

You're the solid proof of that statement.

[Figure-8]

What's more, is that they've found cannabis to be helpful not only with inducing hunger, but that it has anti-tumor properties.

So this information is currently understood as publicly acceptable, in the medical science community. It has been for some time. It has at least been known since the early 1900s...

There are various terpenes in medical marijuana that has been studied and found to be the same terpenes that are found in other plants and herbs. For instance, a medical marijuana strain with lemon or citrus will contain the same terpenes that are found in the lemon or citrus plants. But it goes farther:

Many plant terpenes act synergistically with other terpenes and some serve to either catalyze or inhibit formation of other compounds within a plant. For example, understanding the role of certain terpenes will allow scientists to manipulate cannabinoids to desired ratios. Some terpenes are said to modulate the physiological and psychoactive effects of cannabis.
Cannabis ususally contains a significant amount of a terpene called beta-caryophyllene (BCP), which contributes to the aroma and flavor. Studies show that this terpene, also found in other legal herbs, spices and food plants (it contributes to the spiciness of black pepper), activates the CB2 receptor and acts as a non-psychoactive anti-inflammatory. Because it binds to a cannabinoid receptor, it is considered a cannabinoid and since the widespread natural plant product beta-caryophyllene is an FDA approved food additive and ingested daily with food, it is the first dietary cannabinoid. Whether this compound is able to modulate inflammatory processes in humans via the endocannabinoid system is yet unknown.

http://berkeleypatientscare.com/2010...-and-cannabis/

Additional research is needed into how these legal compounds participate in providing medicinal properties to marijuana. However, unjust Schedule I classification makes it illegal to extract perfectly legal compounds from the cannabis plant in a lab.

Limonene is another terpene. It is a colourless liquid at room temperatures with an extremely strong smell of oranges. According to an article in Cannabis Science, limonene can induce ‘relaxation’ and has it’s own unique pharmacology. It takes its name from the lemon because lemon and other citrus fruits contain high quantities of this compound, which is responsible for much of their smell. Interestingly, it has been considered as a bio-fuel as it is combustible when pure. It is also present in many cannabis strains.

http://localproductco.com/2012/02/04...cal-marijuana/

Terpenes are a vast and varied class of hydrocarbons. Hydrocarbons are made up of hydrogen and carbon and are produced by a diverse selection of plants and insects. They are referred to as terpernoids when they become denatured by oxidation, which is much like being dried and cured. This also happens when they become chemically distorted by rearranging the carbon skeleton.
Terpenes are the main component of any plant’s resin or important oils. They play a huge role in the plant’s vitality and are the foundation for more complex molecules to build such as cannabinoids, different hormones, pigments, vitamins and sterols.

So what we have here is a naturally occurring combination of mental, physical and emotional effects that work through aromatherapy and interaction with the chemical receptor sites. It is a natural medicine that carries a wide range of synergies and therapeutic effects that extend into a psychotherapy and even meditative uses.

It's positive effects have been known for a while. That is important. That is why there is a growing medical marijuana foundation around the country and world.

[kingOfCrash]

Heavy teenage cannabis use linked with anxiety disorders in late 20s
http://ndarc.med.unsw.edu.au/news/he...rders-late-20s