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Old 02-25-2009, 10:01 PM
IDONTSLEEP IDONTSLEEP is offline
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Default Phenylephrine

Hey,

Just wondering if anyone has any experience with Phenylephrine?, I've already UTFSE so no prevail.

SWIM acquired some and wants to know if there is a potential for a synch to E.
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Old 02-25-2009, 10:05 PM
alex333 alex333 is offline
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Default Re: Phenylephrine

im guessing just about everybody has had experience with it, seeing as its one of the main ingredients in most OTC cold/sinus/other meds.

Last edited by alex333; 03-03-2009 at 01:31 AM.
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Old 02-25-2009, 10:14 PM
Hydroponichronic Hydroponichronic is offline
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Default Re: Phenylephrine

Quote:
Originally Posted by IDONTSLEEP View Post
Hey,

Just wondering if anyone has any experience with Phenylephrine?, I've already UTFSE so no prevail.

SWIM acquired some and wants to know if there is a potential for a synch to E.
Well, assuming your not a troll (naive of me), there's no good way to make it E. Matter of fact, there's not even close of a good way to make E out of it. Take a look at the molecules. You might be able to make something recreational if you methylated the phenol and reduced away the B-hydroxy (or maybe oxidized to the ketone, if you're lazy), but probably not.
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Old 02-25-2009, 10:43 PM
IDONTSLEEP IDONTSLEEP is offline
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Default Re: Phenylephrine

Quote:
Originally Posted by Hydroponichronic View Post
Well, assuming your not a troll (naive of me), there's no good way to make it E. Matter of fact, there's not even close of a good way to make E out of it. Take a look at the molecules. You might be able to make something recreational if you methylated the phenol and reduced away the B-hydroxy (or maybe oxidized to the ketone, if you're lazy), but probably not.
Thank you sir
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Old 02-26-2009, 02:24 AM
Hydroponichronic Hydroponichronic is offline
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Default Re: Phenylephrine

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Originally Posted by IDONTSLEEP View Post
Thank you sir
Believe it or not, there was a time when I didn't know the ropes, and as such I asked questions that made people think I was a troll. I also had a different alias then, which will go undeclared, but it all comes down to reading for hundreds and hundreds of hours on organic chem and the like. I wished someone could have spoon-fed me how to cook teh mefs and such, but it can't happen. Someone who knows nothing (or not enough) will always find a way to screw up even the most simple procedure. I could rant on, but I won't.


Anywho...
GL/HF
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Old 02-26-2009, 09:13 AM
fcknut fcknut is offline
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Default Re: Phenylephrine

Quote:
Originally Posted by Hydroponichronic View Post
Well, assuming your not a troll (naive of me), there's no good way to make it E. Matter of fact, there's not even close of a good way to make E out of it. Take a look at the molecules. You might be able to make something recreational if you methylated the phenol and reduced away the B-hydroxy (or maybe oxidized to the ketone, if you're lazy), but probably not.
Well... You could oxidise the alcohol, allowing deprotonation at the alpha position. Methylation of the enolate then reduction of the ketone with something pokey would get you down to meta-hydroxy mef. Dunno if that'll do anything to those receptors, but maybe...
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Old 02-28-2009, 12:59 AM
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nshanin nshanin is offline
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Default Re: Phenylephrine

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Originally Posted by fcknut View Post
Well... You could oxidise the alcohol, allowing deprotonation at the alpha position. Methylation of the enolate then reduction of the ketone with something pokey would get you down to meta-hydroxy mef. Dunno if that'll do anything to those receptors, but maybe...
Meta-methoxy perhaps, but m-hydroxy alone is useless in the amphetamines AFAIK.
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