Re: Isopropyl alchol as solvent for synthetic cannaboids?
Originally Posted by rider
Can I safely use Isopropyl Alcohol as a solvent for infusing some spice with synthetic canaboids?
Yes, I'd recommend 91% or above. I believe it'd be more soluble than JWH-018 in a polar solvent such as ethanol or isopropanol. Oh, and make sure you read the back of the bottle and check that the only ingredients are isopropanol and water: you specifically want to avoid denatonium benzoate (I've never seen it as an additive in the U.S.)
Here's why I say so:
JWH-018, pictured above, is, I believe, soluble in strongly polar solvents due to the presence of oxygen and nitrogen (and is therefore more likely to engage in hydrogen bonding). Hydrogen bonding is what makes water special.
RCS-4, containing a tertiary amine (the nitrogen), a ketone (the doubly bonded oxygen in the middle), and a methoxy group (the oxygen on the far right) allow the molecule to be more miscible in a polar solvent like a simple alcohol. Moar hydrogen bonding due to the extra exposed oxygen = greater solubility in polar solvents over -018.