Totse.com is no longer available!
This is a static archive of what the website used to be.
Check out the new articles and visit the community at Zoklet.net
 
About
Community
Bad Ideas
Drugs
Booze - The Legal Drug
Legal Issues of Drug Use
Marijuana
Miscellaneous Drug Information
Nitrous
OTC Drugs and Household Items
Psychedelics
Rare and Exotic Drugs
Speedy Drugs
Ego
Erotica
Fringe
Society
Technology
register | bbs | search | rss | faq | about
meet up | add to del.icio.us | digg it

Dangerous Combinations


NOTICE: TO ALL CONCERNED Certain text files and messages contained on this site deal with activities and devices which would be in violation of various Federal, State, and local laws if actually carried out or constructed. The webmasters of this site do not advocate the breaking of any law. Our text files and message bases are for informational purposes only. We recommend that you contact your local law enforcement officials before undertaking any project based upon any information obtained from this or any other web site. We do not guarantee that any of the information contained on this system is correct, workable, or factual. We are not responsible for, nor do we assume any liability for, damages resulting from the use of any information on this site.

From Legal Highs by The Twentieth Century Alchemist, published sometime in the early 1970's:

DANGEROUS COMBINATIONS

Unless one is very experienced in pharmacology, it is unwise to experiment with combinations of drugs. Even when using a single drug, thought should be given to all substances, both food and drug, which have been taken recently. Most primitive people fast or at least abstain from certain substances for several days prior to taking a sacrament. Substances most universally avoides are alcohol, coffee, meat, fat and salt. Some drugs potentiate others. For example, atropine will increase the potency of mescaline, harmine, cannabis and the opiates. Many of the substances discussed in this book are MAO inhibitors. MAO (monoamine oxidase) is and enzyme produced in the body which breaks down certain amines and renders them harmless and ineffective. An MAO inhibitor interferes with the protective enzyme and leaves the body vulnerable to these amines. A common substance such as tyramine, which is usually metabolized with little or no pharmacological effect, may become dangerous in the presence of an MAO innhibitor and cause headache, stiff neck, cardiovascular difficulties, and even death. MAO inhibitors may intensify and prolong the effects of other drugs (CNS depressants, narcotic analgesics, anticholinergics, dibenzazepine antidepressants, etc.) by interfering with their metabolism. In the presence of an MAO inhibitor many substances which are ordinarily non-active because of their swift metabolism may become potent psychoactive drugs. This phenomenon may creat a new series of mind alterants. However, because of the complex and precarious variables involved, it is risky and foolish for anyone to experiment with these possibilities on the non-professional level.

The most commonly used MAO inhibitors include hydrazines such as iproniazid, Marsilid, Marplan, Niamid, Nardil, Catron; also non-hydrazines such as propargylamines, cyclopropylamines, aminopyrazine derivatives, indolealkylamines, and carbolines. MAO inhibiting materials discussed in this book include yohimbine, various tryptamines, especially 5-MeO-DMT and the alpha-methyltryptamines, and the various harmala alkaloids. The latter are especially potent inhibitors, but, like yohimbine and the tryptamines, are short-lasting in action (30 minutes to several hours). Some of the commercial MAO inhibitors listed above are effective for several days to several weeks.

Among the material which may be dangerous in combination with MAO inhibitors are sedatives, tranquilizers, antihistamines, narcotics and alcohol--any of which can cause hypotensive crises (severe blood pressure drop); and amphetamines (even diet pills), mascaline, asarone, nutmeg (active doses), macromerine, ephedrine, oils of dill, parsley or wild fennel, beer, wine, cocoa, aged cheeses and other tyrosine-containing foods (tyrosine is converted to tyramine by bacteria in the bowel)--any of which can cause hypertensive crises (severe blood pressure rise).

 
To the best of our knowledge, the text on this page may be freely reproduced and distributed.
If you have any questions about this, please check out our Copyright Policy.

 

totse.com certificate signatures
 
 
About | Advertise | Bad Ideas | Community | Contact Us | Copyright Policy | Drugs | Ego | Erotica
FAQ | Fringe | Link to totse.com | Search | Society | Submissions | Technology
Hot Topics
hot naptha bath
Oxycodone from Codeine
yes another nano thread...
hughjorgen + annie
Extraction of menthol from petroleum jelly
epinephrine inhaler?
Pesticide synth
the raid thread
 
Sponsored Links
 
Ads presented by the
AdBrite Ad Network

 

 

TSHIRT HELL T-SHIRTS